Sickle cell anemia symptoms caused by low red blood cell count include the following: Fatigue and weakness Dizziness Pallor paleness Cold extremities hands and feet , low body temperature Jaundice yellowing of the skin or the whites of the eyes Pain - sudden acute or long-lasting chronic , ranging from mild to severe - is a common symptom of sickle cell anemia.
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It generally attacks lungs,lymph system,circulatory system.